光寻址电位传感器的正交相位检波检测方法

光寻址电位传感器的幅度检测方法易受噪声干扰,灵敏度差,信噪比和精度低,且受调制光源的影响较大,影响检测结果的准确性.为此提出了一种基于正交相位检波的光寻址电位传感器检测方法.该方法是将光寻址电位传感器的输出光电流信号分别与两路正交信号相乘,通过低通滤波提取直流分量并相除,即可得到光寻址电位传感器的输出信号相位信息.与已有的光寻址电位传感器相位检测方法相比,该方法具有算法复杂度低、实时性高的优点.实验研究了调制光源光强对光寻址电位传感器幅度检测和相位检测的影响,对比分析了光寻址电位传感器的传统幅度检测方法与正交相位检波检测方法对pH检测的灵敏度、线性度及信噪比.结果表明,相比于幅度检测方法,调制光源光强对光寻址电位传感器的相位检测影响更小,在频率为10 kHz,pH的范围为1.68~10.01的情况下,相位检测方法比幅度检测方法测得的灵敏度增加了7 mV/pH,精度提高了14.9 mpH,非线性误差减小了0.003%,均方差减少了0.1051×10^-5,信噪比增加了8.2827 dB.该方法特别适用于弱光下的光寻址电位传感器检测.     

基于非共轴阵列照明的小型化眼底相机光学系统设计

建立了非共轴阵列照明下的眼底成像数学模型,采用照明光路与成像光路独立设计方法,提出了一种微小型眼底相机光学系统,以避免传统眼底相机中人眼角膜与网膜物镜反射杂光对视网膜图像的干扰.设计了6阵列环形光源照明光路系统,长度仅17.9 mm,实现眼底视网膜有效照明线视场不小于12 mm;成像光路系统采用二次成像设计,光学调制传递函数优于0.2@91 lp/mm,畸变小于5%,长度仅为75 mm.仿真与设计结果表明,该眼底相机光学系统有效抑制了光路中的杂散光,有利于获得高对比度视网膜图像.研究结果可为高像质、小型化以及低杂光眼底相机发展提供设计参考.     

Kirchberg’s conjecture in the system of Hilbert space factorable mapping spaces

This study aims to introduce the notions of injectivity, local reflexivity, exactness, and nuclearity in the system(Γ_2~c(·, ·), γ_2~c(·)). We find that every dual operator space is injective in the system(Γ_2~c(·, ·), γ_2~c(·)) and nuclearity is equivalent to exactness in this system. As a corollary, we prove that Kirchberg's conjecture on the equivalence of exactness and local reflexivity for C*-algebras is false in this system, i.e., there exists a C*-algebra A that is locally reflexive in this system but is not exact in this system.     

Measurement Uncertainty and Its Connection to Quantum Coherence in an Inertial Unruh–DeWitt Detector

The dynamic characteristics of measured uncertainty and quantum coherence are explored for an inertial Unruh–DeWitt detector model in an expanding de Sitter space. Using the entropic uncertainty relation, the uncertainty of interest is correlated with the evolving time t, the energy level spacing δ, and the Hubble parameter H. The investigation shows that, for short time, a strong energy level spacing and small Hubble parameter can result in a relatively small uncertainty. The evolution of quantum coherence versus the evolving time and Hubble parameter, which varies almost inversely to that of the uncertainty, is then discussed, and the relationship between uncertainty and the coherence is explicitly derived. With respect to the l₁ norm of coherence, it is found that the environment for the quantum system considered possesses a strong non-Markovian property. The dynamic behavior of coherence non-monotonously decreases with the growth of evolving time. The dynamic features of uncertainty and coherence in the expanding space with those in flat space are also compared. Furthermore, quantum weak measurement is utilized to effectively reduce the magnitude of uncertainty, which offers realistic and important support for quantum precision measurements during the undertaking of quantum tasks.     

Polypyrrole modified hierarchical porous CoS2@RGO aerogel electrode for ultrafast sodium storage

Journal of Solid State Electrochemistry - CoS2 nanooctahedrons homogeneously encapsulated by hierarchical porous-reduced graphene oxide and polypyrrole thin film are constructed via a simple...     

A novel LC–MS/MS method for the determination of ziritaxestat in rat plasma and its pharmacokinetic study

Ziritaxestat is a first-in-class autotoxin inhibitor. The purpose of this study was to develop a liquid chromatography/electrospray ionization tandem mass spectrometric (LC–MS/MS) method for the determination of ziritaxestat in rat plasma. The plasma sample was deproteinated using acetonitrile and then separated on an Acquity BEH C₁₈ column with water containing 0.1% formic acid and acetonitrile as mobile phase, which was delivered at 0.4 ml/min. Ziritaxestat and the internal standard (crizotinib) were quantitatively monitored with precursor-to-product transitions of m/z 589.3 > 262.2 and m/z 450.1 > 260.2, respectively. The total running time was 2.5 min. The method showed excellent linearity over the concentration range 0.5–2000 ng/ml, with correlation coefficient >0.9987. The extraction recovery was >82.09% and the matrix effect was not significant. Inter- and intra-day precisions (RSD) were <11.20% and accuracies were in the range of −8.50–7.45%. Ziritaxestat was demonstrated to be stable in rat plasma under the tested conditions. The validated LC–MS/MS method was successfully applied to study the pharmacokinetic profiles of ziritaxestat in rat plasma after intravenous and oral administration. Pharmacokinetic results demonstrated that ziritaxestat displayed a short half-life (~3 h) and low bioavailability (20.52%).     

Dimeric Manganese-Catalyzed Hydroarylation and Hydroalkenylation of Unsaturated Amides

An unprecedented Mn(I)-catalyzed selective hydroarylation and hydroalkenylation of unsaturated amides with commercially available organic boronic acids is reported. Alkenyl boronic acids have been successfully employed for the first time in Mn(I)-catalyzed carbon–carbon bond formation. A wide array of β-alkenylated amide products can be obtained in moderate to good yields, which offers practical access to five- and six-membered lactams. This protocol has predictable regio- and chemoselectivity, excellent functional group compatibility and ease of operation in air, representing a significant step-forward towards manganese-catalyzed C−C coupling.     

2,6-二甲基-3,5-二(吡唑-3-基)吡啶/铜构筑的一维链状Keggin型杂多酸盐的合成、结构及电化学性质研究

以二水氯化铜(CuCl2·2H2O)、硅酸钠(Na2SiO3)、钼酸钠(Na2 MoO4)和2,6-二甲基-3,5-二(吡唑-3-基)吡啶(简写为H2L)为原料,通过水热反应,成功地合成了一个一维链状Keggin型多酸基杂化化合物[Cu2(H3L)2](SiMo12O40).通过X-射线单晶衍射、TGA、IR以及元素分析对该化合物的结构进行表征.测试结果表明,该化合物属于三斜晶系,P-1空间群,晶胞参数a=1.1689(5) nm,b=1.2157(5) nm,c=1.2233(5) nm,α=62.066(5)°,β=62.833(5)°,γ =74.789(5)°,V=1.363 8(10) nm3,Z=2,R1=0.082 4,wR2=0.174 5.电化学分析结果表明该化合物对亚硝酸盐的还原具有良好的电催化效果.     

铅基堆超临界CO2复合循环发电系统热力学分析

本文对比了再压缩超临界CO2 (S-CO2)循环、蒸汽朗肯循环、He布雷顿循环分别应用于铅基堆的最优热学性能,明确了S-CO2循环与铅基堆结合较传统循环的热力学优势。为进一步提高再压缩S-CO2循环的效率,以跨临界CO2 (T-CO2)循环为底循环构建了再压缩S-CO2/T-CO2复合循环,探讨了不同顶循环透平入口温度、压力和压缩机入口温度条件下系统性能的变化规律,对比了S-CO2/T-CO2复合循环和S-CO2循环的热学性能。结果表明:铅基堆再压缩S-CO2循环发电系统较传统循环形式具有更高的热效率;构建的S-CO2/T-CO2复合循环能够有效提高S-CO2循环的效率,在所研究参数范围内,S-CO2/T-CO2复合循环的热效率和效率比S-CO2循环分别最大可提高约4.8%和8.3%;再压缩S-CO2循环和S-CO2/T-CO2复合循环热学性能随顶循环关键参数变化规律具有一致性。